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Home Antibody All anti-DOK1 antibodies

Anti-DOK1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305939
  • Rabbit Polyclonal DOK1 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419987) , 20ug
100ug $325 3-7 Days
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WB(1)
IF(1)
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Also for DOK1 (NM_001381)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDOK1 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DOK1.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 2 ug/ml, IF: 10 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens docking protein 1, 62kDa (downstream of tyrosine kinase 1) (DOK1), transcript variant 1
Alternative NameP62DOK
Database LinkNP_001372
FunctionSignals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptor tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors was identified recently from human and mouse by several laboratories. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok represents a new family with very recently identified p56dok.
Related Pathway

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WB Image
Western blot analysis of DOK1 in Jurkat (Jur) and THP-1 (THP) cell lysates with DOK1 antibody at 1 ug/mL.
IF Image
Immunocytochemistry of DOK1 in K562 cells with DOK1 antibody at 2 ug/mL.

 

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