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Home Antibody All anti-DNMT3A antibodies

Anti-DNMT3A Antibody EPR2408

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306992
  • Rabbit monoclonal antibody against Dnmt3a(clone EPR2408)
100ul $325 3-7 Days
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WB(1)
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Also for DNMT3A (NM_175629)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Dnmt3a was used as an immunogen.
Clone NameEPR2408 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
Purification Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens DNA (cytosine-5-)-methyltransferase 3 alpha (DNMT3A), transcript variant 1
Alternative NameDNMT3A2; M.HsaIIIA
Database LinkNP_783328
FunctionCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus; its expression is developmentally regulated.
Related Pathway

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WB Image
Western blot - Anti-Dnmt3a antibody [EPR2408]; All lanes : Anti-Dnmt3a antibody [EPR2408] at 1/1000 dilution.Lane 1 : SH SY5Y cell lysate.Lane 2 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 102 kDa.

 

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