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Home Antibody All anti-DNM1L antibodies

Anti-DNM1L Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA301511 Rabbit Polyclonal Antibody against DRP1 100ul $325 In Stock
LC402138 DNM1L HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for DNM1L (NM_012062)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide made to an internal region within residues 500-600 of the human protein. [Swiss-Prot# O00429]
Clone Name IsotypeIgG
Species Reactivityhuman, primate, rat, mouse, hamster ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1: 1000
BufferTris-glycine, 150mM NaCl and 0.5% sodium azide
Purification Immunogen affinity purified

Reference Data

Target NameHomo sapiens dynamin 1-like (DNM1L), transcript variant 1
Alternative NameDLP1; DRP1; DVLP; DYMPLE; EMPF; HDYNIV
Database LinkNP_036192
Entrez Gene 10059 Human
Entrez Gene 74006 Mouse
Entrez Gene 114114 Rat
FunctionA human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses.
Related Pathway EndocytosisFc gamma R-mediated phagocytosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Lane 1: DRP1 knockout, Lane 2: DRP1 wildtype MEFs at 1:500x dilution
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Staining of renal tubular epithelium and visceral epithelial cells of the glomerulus at 2.5ug/ml. Human kidney cortex, 40X magnification
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Immunocytochemistry/Immunofluorescence: DRP1 antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).
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