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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-DNASE1 antibodies

Anti-DNASE1 Antibody

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SKU Description Amount Price Availability*  
TA308546
  • Rabbit Polyclonal antibody to DNase I (deoxyribonuclease I)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401601) , 20ug
 100ul $325 3-7 Days Add to Shopping Cart
WB(1)
IF(1)
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Also for DNASE1 (NM_005223)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody
Gene NameHomo sapiens deoxyribonuclease I (DNASE1)
Synonyms:DNL1; DRNI
ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 252 of DNase I
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Purification Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:500;
BackgroundThis gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]
Related Pathway

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WB Image
Sample (30 ug of whole cell lysate) A: MOLT4 (anti-DNASE1 antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using DNase I(anti-DNASE1 antibody) antibody at 1:200 dilution.

 

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