Home Antibody All anti-DMBT1 antibodies
Also for DMBT1 (NM_004406)
|Recombinant fragment corresponding to a region within amino acids 2035 and 2313 of gp340 (Uniprot ID#Q9UGM3)|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens deleted in malignant brain tumors 1 (DMBT1), transcript variant 1|
Entrez Gene 1755 Human
|Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq]|
|Druggable Genome |
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Sample (30 ug of whole cell lysate). A: H1299. 5% SDS PAGE. TA308337 diluted at 1:1000