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Home Antibody All anti-DMBT1 antibodies

Anti-DMBT1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308337
  • Rabbit polyclonal antibody to gp340 (deleted in malignant brain tumors 1)
100ul 325 In Stock
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WB(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 2035 and 2313 of gp340 (Uniprot ID#Q9UGM3)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 260kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens deleted in malignant brain tumors 1 (DMBT1), transcript variant 1
Alternative NameGP340; muclin
Database LinkNP_004397
Entrez Gene 1755 Human
FunctionLoss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: H1299. 5% SDS PAGE. TA308337 diluted at 1:1000

 

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