VEGFA Mouse Monoclonal Antibody [Clone ID: VG1]

CAT#: DM308-05

VEGFA mouse monoclonal antibody, clone VG1, Purified

Product Images

Formalin fixed paraffin embedded human angiosarcoma stained with VEGF antibody DM308 / DM308-05

Specifications

Product Data

• Clone Name: VG1
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Embedded Sections: use a dilution of 1/20-1/40 with Polymer Detection systems such as our UnoVue or PolyVue systems.
  Incubation Time: 30 minutes at RT.
  High temperature treatment of formalin-fixed tissue sections using 1mM EDTA, pH 8.0 must be performed prior to the immunostaining.
  Recommended Positive Control: Astrocytoma
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant VEGF protein
• Specificity: This antibody is specific to a cluster of proteins between 19-22 kD (reduced).
  Cellular Localization: Cytoplasmic, cell membrane, extracellular matrix.
• Formulation: State: Purified
  State: Liquid purified Ig fraction containing Sodium Azide as preservative
• Purification: Protein G Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: vascular endothelial growth factor A
• Database Link:
  Entrez Gene 7422 Human
  UniProt ID P15692
• Background: VEGF is a homodimeric disulfide-linked glycoprotein involved in angiogenesis, which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability inducing properties specific for the vascular endothelium.
• Synonyms: VEGFA, VEGF, VPF, Vascular endothelial growth factor A, Vascular permeability factor