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Home Antibody All anti-DKK1 antibodies

Anti-DKK1 Antibody EPR4759

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307798 Rabbit monoclonal antibody against DKK1(clone EPR4759) 100ul $325 In Stock
LC402176 DKK1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DKK1 was used as an immunogen.
Clone NameEPR4759 IsotypeIgG
Species ReactivityRat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; FC: 1:100 - 1:500; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 29 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens dickkopf WNT signaling pathway inhibitor 1 (DKK1)
Alternative NameDKK-1; SK
Database LinkNP_036374
Entrez Gene 22943 Human
Entrez Gene 293897 Rat
FunctionDKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood are associated with the presence of osteolytic bone lesions in patients with multiple myeloma (1).
Related PathwayStem cell relevant signaling - Wnt Signaling pathwaySecreted ProteinES Cell Differentiation/IPSAdult stem cellsCancer stem cellsDruggable Genome Wnt signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - DKK1 antibody [EPR4759]; All lanes : Anti-DKK1 antibody [EPR4759] at 1/1000 dilution.Lane 1 : JAR cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : NCCIT cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 29 kDa.Observed band size : 38 kDa .
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DKK1 antibody [EPR4759]; Immunohistochemical analysis of paraffin-embedded Human placenta tissue using 1/100 TA307798
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Immunocytochemistry/ Immunofluorescence - DKK1 antibody [EPR4759]; Immunofluorescent staining of HeLa cells using 1/100 TA307798
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