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Anti-DKK1 Antibody EPR4759
Also for DKK1 (NM_012242)
|A synthetic peptide corresponding to residues in human DKK1 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
|WB, IHC, IF
||WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; FC: 1:100 - 1:500; ICC/IF: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for IP.
|Homo sapiens dickkopf WNT signaling pathway inhibitor 1 (DKK1)|
|DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood are associated with the presence of osteolytic bone lesions in patients with multiple myeloma (1).|
Wnt Signaling Pathway
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Western blot - DKK1 antibody [EPR4759]; All lanes : Anti-DKK1 antibody [EPR4759] at 1/1000 dilution.Lane 1 : JAR cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : NCCIT cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 29 kDa.Observed band size : 38 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DKK1 antibody [EPR4759]; Immunohistochemical analysis of paraffin-embedded Human placenta tissue using 1/100 ab109416
Immunocytochemistry/ Immunofluorescence - DKK1 antibody [EPR4759]; Immunofluorescent staining of HeLa cells using 1/100 ab109416