OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-DFFA antibodies

Anti-DFFA Antibody EPR4222(2)

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307302
  • Rabbit monoclonal antibody against DFF45/DFF35(clone EPR4222(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418008) , 20ug Explanation
100ul 325 3-7 Days
Add to Shopping Cart
spacer
WB(1)
spacer
Also for DFFA (NM_004401)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DFF45/DFF35 was used as an immunogen.
Clone NameEPR4222(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:10000 - 1:50000
Predicted MW Explanation 37 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1
Alternative NameDFF-45; DFF1; ICAD
Database LinkNP_004392
Entrez Gene 1676 Human
Entrez Gene 13347 Mouse
Entrez Gene 114214 Rat
FunctionDNA fragmentation factor (DFF) is a heterodimeric protein of 40-kDa (DFF40) and 45-kDa (DFF45) subunits. DFF45 is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFF45 is cleaved by caspase-3. The cleaved fragments of DFF45 dissociate from DFF40, the active component of DFF. DFF40 has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. DFF35 is the short isoform of DFF45.
Related Pathway Apoptosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - ICAD antibody [EPR4222(2)]; All lanes : Anti-ICAD antibody [EPR4222(2)] at 1/10000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : U937 cell lysate.Lane 3 : A431 cell lysate.Lane 4 : A549 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 37 kDa.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title