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Home Antibody All anti-DES antibodies

Anti-DES TRUEMAB Antibody clone 4G1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502328
  • DES (Desmin ) mouse monoclonal antibody, clone 4G1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400713) , 20ug Explanation
100ul $379 In Stock
CF502328
  • Carrier-free (BSA/glycerol-free) DES mouse monoclonal antibody, clone 4G1
100ug $450 8-10 Days
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WB(1)
IHC(5)
FC(1)

OriGene Data

ImmunogenHuman fragment corresponding to amino acids 104-391 of human DES (NP_001918) produced in E.coli.
Clone Nameclone 4G1 IsotypeIgG1
Species ReactivityHuman Concentration0.63 mg/ml
Guaranteed Application *WB, IHC, FC Suggested Dilutions WB 1:200~500, IHC 1:150, FLOW 1:100,
Predicted MW Explanation 53.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens desmin (DES)
Alternative NameCSM1; CSM2; LGMD2R
Database LinkNP_001918
Entrez Gene 1674 Human
FunctionThis gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome Hypertrophic cardiomyopathy (HCM)Arrhythmogenic right ventricular cardiomyopathy (ARVC)Dilated cardiomyopathy

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DES (RC205685, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DES.
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Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-DES mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502328)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-DES mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502328)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-DES mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502328)
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Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-DES mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502328)
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-DES mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502328)
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HEK293T cells transfected with either RC205685 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-DES antibody(TA502328), and then analyzed by flow cytometry.
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