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Home Antibody All anti-DES antibodies

Anti-DES Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA305636 Goat Anti-Desmin Antibody 100ug $325 In Stock
LC400713 DES HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenPeptide with sequence C-RDGEVVSEATQQQHE, from the C Terminus of the protein sequence according to NP_001918.3.
Clone Name IsotypeGoat IgG
Species ReactivityTested: Human, Mouse, Rat, Pig. Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.1-0.3 µg/ml. IHC: 3-6 µg/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens desmin (DES)
Alternative NameCSM1; CSM2; LGMD2R
Database LinkNP_001918
Entrez Gene 1674 Human
Entrez Gene 13346 Mouse
Entrez Gene 64362 Rat
Entrez Gene 497091 Dog
FunctionThis gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq].
Related PathwayDruggable Genome Hypertrophic cardiomyopathy (HCM)Arrhythmogenic right ventricular cardiomyopathy (ARVC)Dilated cardiomyopathy

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA305636 (0.5 ug/ml) staining of Pig (A), Mouse (B) and Rat (C) Skeletal Muscle lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

IHC Image
TA305636 (3.8 ug/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.


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