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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-DEF6 antibodies

Anti-DEF6 TrueMAB Antibody Clone 2G2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA505351
  • Purified DEF6 mouse monoclonal antibody,clone 2G2
  • FREE positive control: HEK293T cell transient overexpression lysate (LC411815) , 20ug
 100ul $325 In Stock Add to Shopping Cart
CF505351
  • Carrier-free (BSA/glycerol-free) DEF6 mouse monoclonal antibody,clone 2G2
100ug $450 8-10 Days Add to Shopping Cart
WB(2)
IHC(2)
IF(1)
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Also for DEF6 (NM_022047)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens differentially expressed in FDCP 6 homolog (mouse) (DEF6)
Synonyms:IBP; SLAT; SWAP70L
ImmunogenFull length human recombinant protein of human DEF6(NP_071330) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 2G2 IsotypeIgG2a
Species ReactivityHuman , Dog , Monkey Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:500~2000, IHC 1:150, IF 1:100,
BackgroundDEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DEF6 (RC217877, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DEF6.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-DEF6 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-DEF6 mouse monoclonal antibody. (TA505351)
IHC Image
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-DEF6 mouse monoclonal antibody. (TA505351)
IF Image
Anti-DEF6 mouse monoclonal antibody (TA505351) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DEF6(RC217877).

 

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