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Anti-DEF6 Antibody EPR7492


Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against DEF6
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC411815) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human DEF6 was used as an immunogen.
Clone NameEPR7492 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC: 1:100 - 1:250; FC: 1:100 - 1:500
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for IHC-P.

Reference Data

Target NameHomo sapiens differentially expressed in FDCP 6 homolog (mouse) (DEF6)
Alternative NameIBP; SLAT; SWAP70L
Database LinkNP_071330
Entrez Gene 50619 Human
FunctionDEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC and CDC42 that is highly expressed in B and T cells (1). It plays a unique role in TCR-mediated signaling pathways and the control of adaptive immune responses (2). DEF6 is also involved in the development and maturation of Th2 cells (3).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-DEF6 antibody [EPR7492]; All lanes : Anti-DEF6 antibody [EPR7492] at 1/1000 dilution.Lane 1 : Human tonsil lysate.Lane 2 : Ramos lysate.Lane 3 : MOLT4 lysate.Lane 4 : Human thymus lysate.Lane 5 : Jurkat lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 74 kDa.
Other-Anti-DEF6 antibody [EPR7492](TA310406); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-DEF6 antibody [EPR7492]; TA310406 at 1/100 dilution staining DEF6 in permeabilized Jurkat cells by Flow cytometry (red) compared with a rabbit IgG negative control (green).


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