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Anti-DDX50 Antibody EPR5273
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Also for DDX50 (NM_024045)
|A synthetic peptide corresponding to residues in human DDX50 was used as an immunogen.|
|Human, Mouse, Rat
||WB: 1:1,000 - 10,000; FC: 1:10 - 100;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 (DDX50)|
|GU2; GUB; mcdrh; RH-II/GuB|
|DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX50 is a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. DDX50 and DDX21, also called RH-II/GuA, have similar structures and are in tandem orientation (1).|
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Western blot analysis on (A) HeLa, (B) 293T, (C) K562, and (D) Jurkat cell lysates using anti-DDX50 RabMAb.
Immunohistochemical analysis of paraffin-embedded human thyroid gland adenocarcinoma tissue using anti-DDX50 RabMAb.