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Home Antibody All anti-DDIT3 antibodies

Anti-DDIT3 TRUEMAB Antibody Clone 2D3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA802218
  • DDIT3 mouse monoclonal antibody,clone 2D3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418226) , 20ug
100ul 325
$245
In Stock
CF802218
  • Carrier-free (BSA/glycerol-free) DDIT3 mouse monoclonal antibody,clone 2D3
100ug $450 3 Days
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WB(1)
IHC(4)

OriGene Data

ImmunogenFull length human recombinant protein of human DDIT3 (NP_004074) produced in E.coli.
Clone NameClone 2D3 IsotypeIgG2a
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:500, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens DNA-damage-inducible transcript 3 (DDIT3), transcript variant 5
Alternative NameCEBPZ; CHOP; CHOP-10; CHOP10; GADD153
Database LinkNP_004074
FunctionThis gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010].
Related Pathway
Adipogenesis
MAPK signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DDIT3 (RC201301, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DDIT3.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-DDIT3 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA802218)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-DDIT3 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA802218)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-DDIT3 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA802218)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-DDIT3 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA802218)

 

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