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Home Antibody All anti-DDIT3 antibodies

Anti-DDIT3 TRUEMAB Antibody Clone3H7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA802210
  • DDIT3 mouse monoclonal antibody,clone 3H7
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418226) , 20ug
100ul $325 In Stock
CF802210
  • Carrier-free (BSA/glycerol-free) DDIT3 mouse monoclonal antibody,clone 3H7
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)

OriGene Data

ImmunogenFull length human recombinant protein of human DDIT3 (NP_004074) produced in E.coli.
Clone NameClone3H7 IsotypeIgG1
Species ReactivityHuman Concentration1.00 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens DNA-damage-inducible transcript 3 (DDIT3), transcript variant 5
Alternative NameCEBPZ; CHOP; CHOP-10; CHOP10; GADD153
Database LinkNP_004074
FunctionThis gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010].
Related Pathway
Adipogenesis
MAPK signaling pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DDIT3 (RC201301, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DDIT3.

 

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