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Home Antibody All anti-DDC antibodies

Anti-DDC Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302469 Goat Polyclonal Antibody against DOPA decarboxylase 100ug $325 3-7 Days
LC421202 DDC HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
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Also for DDC (NM_001082971)
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OriGene Data

ImmunogenPeptide with sequence C-WEHIKELAADVL, from the C Terminus of the protein sequence according to NP_000781.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:8,000. WB: 0.03-0.1µg/ml.
Predicted MW Explanation 57522Da
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens dopa decarboxylase (aromatic L-amino acid decarboxylase) (DDC), transcript variant 1
Alternative NameAADC
Database LinkNP_001076440
Entrez Gene 1644 Human
FunctionThe encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Histidine metabolismTyrosine metabolismPhenylalanine metabolismTryptophan metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA302469 (0.03µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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