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Home Antibody All anti-DDB1 antibodies

Anti-DDB1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308812
  • Rabbit Polyclonal antibody to DDB1 (damage-specific DNA binding protein 1, 127kDa)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419658) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 749 and 1123 of DDB1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.81mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:1000-1:10000; IHC:1:500; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens damage-specific DNA binding protein 1, 127kDa (DDB1)
Alternative NameDDBA; UV-DDB1; XAP1; XPCE; XPE; XPE-BF
Database LinkNP_001914
FunctionThis gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq]
Related Pathway

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WB Image
Sample (30 ug of whole cell lysate) A: HepG2 (anti-DDB1 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft , using DDB1(anti-DDB1 antibody) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using DDB1(anti-DDB1 antibody) antibody at 1:200 dilution.

 

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