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Home Antibody All anti-DCTN3 antibodies

Anti-DCTN3 Antibody EPR5097

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310399
  • Rabbit Monoclonal antibody against DCTN3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416118) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(1)
Assay(1)
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Also for DCTN3 (NM_007234)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DCTN3 was used as an immunogen.
Clone NameEPR5097 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
Predicted MW Explanation 21 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens dynactin 3 (p22) (DCTN3), transcript variant 1
Alternative NameDCTN-22; DCTN22
Database LinkNP_009165
Entrez Gene 11258 Human
Entrez Gene 53598 Mouse
Entrez Gene 362504 Rat
FunctionDCTN3 is the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. DCTN3 is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-DCTN3 antibody [EPR5097]; All lanes : Anti-DCTN3 antibody [EPR5097] at 1/1000 dilution.Lane 1 : 293T cell lysates.Lane 2 : Mouse muscle lysates.Lane 3 : HeLa cell lysates.Lane 4 : BxPC 3 cell lysates.Lane 5 : SH-SY5Y cell lysates.Lane 6 : Rat muscle lysates.Lysates/proteins at 10 ug per lane.Secondary.Lanes 1, 2, 3, 5 & 6 : Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 21 kDa.
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Other-Anti-DCTN3 antibody [EPR5097](TA310399); Equilibrium disassociation constant (KD)..
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DCTN3 antibody [EPR5097]; TA310399, at 1/100 dilution, staining DCTN3 in paraffin embedded Human breast tissue by Immunohistochemistry.
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