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Anti-DAZL Antibody EPR5140
Also for DAZL (NM_001351)
|A synthetic peptide corresponding to residues in human DAZL was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens deleted in azoospermia-like (DAZL), transcript variant 2|
|DAZH; DAZL1; DAZLA; SPGYLA|
|The DAZ (Deleted in AZoospermia) family are potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. DAZL is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of DAZL during primate evolution gave rise to DAZ on the Y chromosome. Mutations in DAZL have been linked to severe spermatogenic failure and infertility in males.|
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Western blot - DAZL antibody [EPR5140]; All lanes : Anti-DAZL antibody [EPR5140] at 1/1000 dilution.Lane 1 : Human testis lysate.Lane 2 : Human small intestine lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 33 kDa.