Home Antibody All anti-DAZ2 antibodies
Also for DAZ2 (NM_020363)
|Recombinant fragment corresponding to a region within amino acids 1 and 237 of DAZ2 (Uniprot ID#Q13117)|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens deleted in azoospermia 2 (DAZ2), transcript variant 1|
Entrez Gene 57055 Human
|This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate). A: Molt-4 . 7.5% SDS PAGE. TA309024 diluted at 1:1000
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using DAZ2(TA309024) antibody at 1:200 dilution.