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Home Antibody All anti-DAPK3 antibodies

Anti-DAPK3 Antibody EPR1635

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307546
  • Rabbit monoclonal antibody against DAPK3 (clone EPR1635 )
100ul 325 3-7 Days
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WB(1)
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Also for DAPK3 (NM_001348)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the N-terminus of human DAPK3 was used as an immunogen.
Clone NameEPR1635 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:5000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens death-associated protein kinase 3 (DAPK3)
Alternative NameDLK; ZIP; ZIPK
Database LinkNP_001339
FunctionDAPK3 (Death-associated protein kinase) is a Ca2+ calmodulin serine/threonine kinase which acts as a positive regulator of apoptosis through its catalytic activities. DAPK3 is a mediator of apoptosis and is induced by gamma interferon (1). Results suggest that DAPK3, in collaboration with Daxx and Par-4, mediates a novel nuclear pathway for apoptosis (2). It has been shown that the nuclear serine/threonine-specific kinase phosphorylates core histones H3 and H4, and myosine light chain in vitro. DAPK3 interacts with transcription and splicing factors as well as with pro-apoptotic protein Par-4 suggesting that it participates in multiple cellular processes (3).
Related Pathway

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WB Image
Western blot - ZIP Kinase antibody [EPR1635]; All lanes : Anti-ZIP Kinase antibody [EPR1635] at 1/5000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : A431 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 53 kDa.Observed band size : 53 kDa.

 

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