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Anti-DAPK3 Antibody EPR1635
Also for DAPK3 (NM_001348)
|A synthetic peptide corresponding to residues on the N-terminus of human DAPK3 was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:5000 - 1:10000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens death-associated protein kinase 3 (DAPK3)|
|DLK; ZIP; ZIPK|
Entrez Gene 1613 Human
|DAPK3 (Death-associated protein kinase) is a Ca2+ calmodulin serine/threonine kinase which acts as a positive regulator of apoptosis through its catalytic activities. DAPK3 is a mediator of apoptosis and is induced by gamma interferon (1). Results suggest that DAPK3, in collaboration with Daxx and Par-4, mediates a novel nuclear pathway for apoptosis (2). It has been shown that the nuclear serine/threonine-specific kinase phosphorylates core histones H3 and H4, and myosine light chain in vitro. DAPK3 interacts with transcription and splicing factors as well as with pro-apoptotic protein Par-4 suggesting that it participates in multiple cellular processes (3). |
|Protein KinaseDruggable Genome Pathways in cancerBladder cancer|
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Western blot - ZIP Kinase antibody [EPR1635]; All lanes : Anti-ZIP Kinase antibody [EPR1635] at 1/5000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : A431 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 53 kDa.Observed band size : 53 kDa.