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Home Antibody All anti-DAPK3 antibodies

Anti-DAPK3 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA305981 Rabbit Polyclonal ZIPK Antibody 100ug $325 In Stock
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WB(1)
IF(1)
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Also for DAPK3 (NM_001348)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenZIP kinase antibody was raised against a peptide corresponding to amino acids near the center of human ZIP kinase.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 10 ug/ml, IF: 10 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens death-associated protein kinase 3 (DAPK3)
Alternative NameDLK; ZIP; ZIPK
Database LinkNP_001339
Entrez Gene 1613 Human
Entrez Gene 13144 Mouse
Entrez Gene 64391 Rat
FunctionApoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase . ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues .
Related PathwayProtein KinaseDruggable Genome Pathways in cancerBladder cancer

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Western blot analysis of ZIP kinase in HeLa (H) and Jurkat (J) whole cell lysates with ZIP kinase antibody at 1 ug/mL.
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Immunocytochemistry of ZIP kinase in Jurkat cells with ZIP kinase antibody at 10 ug/mL.
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