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Home Antibody All anti-DAP antibodies

Anti-DAP Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319633 Rabbit Polyclonal DAP Antibody 100ug $325 In Stock
LC418020 DAP HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenDAP antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DAP.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 - 2 ug/ml
Predicted MW Explanation Predicted: 11 kDa Observed: 11 kDa
BufferDAP Antibody is supplied in PBS containing 0.02% sodium azide.
Purification DAP Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens death-associated protein (DAP), transcript variant 2
Alternative NameMGC99796
Database LinkNP_004385
Entrez Gene 1611 Human
Entrez Gene 223453 Mouse
Entrez Gene 64322 Rat
FunctionDAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of DAP in human small intestine tissue lysate with DAP antibody at 1 ug/mL.
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