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Anti-DAND5 TRUEMAB Antibody Clone OTI3A3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA503713 DAND5 mouse monoclonal antibody, clone OTI3A3 (formerly 3A3) 100ul 325
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CF503713 Carrier-free (BSA/glycerol-free) DAND5 mouse monoclonal antibody, clone OTI3A3 (formerly 3A3) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 23-189 of human DAND5(NP_689867) produced in E.coli.
Clone NameClone OTI3A3 IsotypeIgG2a
Species ReactivityHuman Concentration4.07 mg/ml
Guaranteed Application *IF, FC Suggested DilutionsIF 1:100, FLOW 1:100,
Predicted MW Explanation 18 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens DAN domain family member 5, BMP antagonist (DAND5)
Alternative NameCER2; CERL2; CKTSF1B3; COCO; CRL2; DANTE; GREM3; SP1
Database LinkNP_689867
Entrez Gene 199699 Human
FunctionThis gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq].
Related Pathway

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IF Image
Anti-DAND5 mouse monoclonal antibody (TA503713) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAND5(RC221703).

FC Image
HEK293T cells transfected with either RC221703 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-DAND5 antibody(TA503713), and then analyzed by flow cytometry.


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