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Home Antibody All anti-DAND5 antibodies

Anti-DAND5 TRUEMAB Antibody Clone 3A3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503713
  • DAND5 mouse monoclonal antibody,clone 3A3
100ul 325 In Stock
CF503713
  • Carrier-free (BSA/glycerol-free) DAND5 mouse monoclonal antibody,clone 3A3
100ug $450 3-4 weeks
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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IF(1)
FC(1)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 23-189 of human DAND5(NP_689867) produced in E.coli.
Clone NameClone 3A3 IsotypeIgG2a
Species ReactivityHuman Concentration4.07 mg/ml
Guaranteed Application *IF, FC Suggested DilutionsIF 1:100, FLOW 1:100,
Predicted MW Explanation 18 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens DAN domain family member 5, BMP antagonist (DAND5)
Alternative NameCER2; CERL2; CKTSF1B3; COCO; CRL2; DANTE; GREM3; SP1
Database LinkNP_689867
Entrez Gene 199699 Human
FunctionThis gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IF Image
Anti-DAND5 mouse monoclonal antibody (TA503713) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAND5(RC221703).
FC Image
HEK293T cells transfected with either RC221703 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-DAND5 antibody(TA503713), and then analyzed by flow cytometry.

 

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