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Home Antibody All anti-DAB2 antibodies

Anti-DAB2 Antibody EPR2249

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307547
  • Rabbit monoclonal antibody against Dab2 (clone EPR2249 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400534) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for DAB2 (NM_001343)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Dab2 was used as an immunogen.
Clone NameEPR2249 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:5000; IP: 1:10; FC: 1:50
BufferDoes not react with Mouse, Rat. Is unsuitable for ICC or IHC-P.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC or IHC-P.

Reference Data

Target NameHomo sapiens Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) (DAB2), transcript variant 1
Alternative NameDOC-2; DOC2
Database LinkNP_001334
FunctionDab2 (Disabled homolog 2, Diabled-2) is a mammalian structural homolog of Drosophila Disabled protein and a mitogen-responsive phosphoprotein (1). As a component of the CSF1 signal transduction pathway, Dab2 is normally expressed in ovarian epithelia cells. However, in ovarian carcinoma, Dab2 expression is either lost or down-regulated. Therefore, Dab2 is speculated to be a negative regulator of growth and its down-regulation considered to play critical role in ovarian carcinogenesis (2).
Related Pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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WB Image
Western blot - Anti-DAB2 antibody [EPR2249]; Anti-DAB2 antibody [EPR2249] at 1/1000 dilution + HeLa cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 82 kDa.

 

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