Home Antibody All anti-Cxcl12 antibodies
Also for Cxcl12 (NM_000609)
|E. coli-expressed mouse SDF-1ß|
||WB: 1:1000-2500, IP
|100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.|
|Homo sapiens chemokine (C-X-C motif) ligand 12 (CXCL12), transcript variant 2|
|IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1|
Entrez Gene 20315 Mouse
Entrez Gene 24772 Rat
|SDF-1ß (stromal cell-derived factor-ß), also known as pre-B-cell growth-stimulating factor (PBSF), is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.|
Cytokine-cytokine receptor interaction
Signaling by GPCR
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Western blot analysis of SDF-1beta expression in transfected cells.