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Home Antibody All anti-Creb1 antibodies

Anti-Creb1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318905
  • Rabbit polyclonal anti-CREB antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418033) , 20ug
100ug $325 3-7 Days
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WB(1)
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Also for Creb1 (NM_004379)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 109 of rat CREB
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml, IHC: 5ug/ml
Buffer100 µg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens cAMP responsive element binding protein 1 (CREB1), transcript variant A
Alternative NameCREB
Database LinkNP_004370
FunctionTranscription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.
Related Pathway
Adipogenesis
EGFR1 Signaling Pathway
Melanogenesis

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WB Image
Western blot analysis of CREB in 3T3 cell lysate.

 

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