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Home Antibody All anti-CYP1A2 antibodies

Anti-CYP1A2 TRUEMAB Antibody clone 8F1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA501196
  • anti-CYP1A2 (Cytochrome P450 1A2) mouse monoclonal antibody, clone 8F1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424529) , 20ug
100ul 379 In Stock
CF501196
  • Carrier-free (BSA/glycerol-free) CYP1A2 mouse monoclonal antibody, clone 8F1
100ug $450 3-4 weeks
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WB(1)
IHC(8)
IF(1)
FC(2)
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Also for CYP1A2 (NM_000761)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human CYP1A2 (NP_000752) produced in HEK293T cell.
Clone Nameclone 8F1 IsotypeIgG2a
Species ReactivityHuman Concentration0.77 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2)
Alternative NameCP12; P3-450; P450(PA)
Database LinkNP_000752
FunctionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP1A2 (RC221636, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP1A2.
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-CYP1A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501196, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CYP1A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501196, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-CYP1A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501196, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-CYP1A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501196, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CYP1A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501196, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-CYP1A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501196, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-CYP1A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501196, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-CYP1A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501196, Dilution 1:50)
IF Image
Anti-CYP1A2 mouse monoclonal antibody (TA501196) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP1A2(RC221636).
FC Image
HEK293T cells transfected with either RC221636 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CYP1A2 antibody(TA501196), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-CYP1A2 antibody(TA501196),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).

 

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