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Home Antibody All anti-CYP17A1 antibodies

Anti-CYP17A1 TRUEMAB Antibody Clone OTI3D9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA503437 CYP17A1 mouse monoclonal antibody, clone OTI3D9 (formerly 3D9) 100ul $325 In Stock
LC400030 CYP17A1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF503437 Carrier-free (BSA/glycerol-free) CYP17A1 mouse monoclonal antibody, clone OTI3D9 (formerly 3D9) 100ug $450 3-4 weeks
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WB(1)
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Also for CYP17A1 (NM_000102)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human CYP17A1(NP_000093) produced in HEK293T cell.
Clone NameClone OTI3D9 IsotypeIgG1
Species ReactivityHuman Concentration0.9 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:500,
Predicted MW Explanation 57.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1)
Alternative NameCPT7; CYP17; P450C17; S17AH
Database LinkNP_000093
Entrez Gene 1586 Human
FunctionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq].
Related PathwayP450Druggable Genome C21-Steroid hormone metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP17A1 (RC209042, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP17A1.
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