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Home Antibody All anti-CTTN antibodies

Anti-CTTN PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA324049
  • Anti-CTTN (Phospho-Tyr466) Rabbit Polyclonal Antibody
100ul $325 2-3 Weeks
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WB(1)
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Also for CTTN (NM_138565)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide sequence around phosphorylation site of tyrosine 466 (P-V-Y(p)-E-T) derived from Human CORTACTIN.
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1000
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens cortactin (CTTN), transcript variant 2
Alternative NameEMS1
Database LinkNP_612632
FunctionCortactin is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene.
Related Pathway

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WB Image
Predicted band size: 85 kDa . Positive control: Jurkat cells treated with H2O2 lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: Jurkat cells untreated with H2O2 lysate Lane2: Jurkat cells treated with H2O2 lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

 

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