Home Antibody All anti-CTSK antibodies
Also for CTSK (NM_000396)
| Peptide with sequence C-KTHRKQYNNKVDE, from the internal region (near N-terminus) of the protein sequence according to NP_000387.1.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow
||ELISA: 1:16,000. WB: 1-3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens cathepsin K (CTSK)|
|CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD|
Entrez Gene 1513 Human
Entrez Gene 13038 Mouse
Entrez Gene 29175 Rat
Entrez Gene 608843 Dog
|The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq]. |
|ProteaseDruggable Genome Lysosome|
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TA303361 (1µg/ml) staining of Human Lung lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.