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Home Antibody All anti-CTNNB1 antibodies

Anti-CTNNB1 Antibody E247

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303471
  • Rabbit monoclonal antibody against ß-catenin(E247)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419662) , 20ug
100ul $325 3-7 Days
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Also for CTNNB1 (NM_001904)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near N-terminus of human ?-catenin was used as immunogen.
Clone NameE247 IsotypeRabbit IgG
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application * Suggested DilutionsWB: 1:5,000-10,000; IHC: 1:500; ICC: 1:250; IP: 1:100
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1
Alternative Namearmadillo; CTNNB; MRD19
Database LinkNP_001895
FunctionBeta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM].
Related Pathway
Adherens junction
Adipogenesis
Focal Adhesion
Melanogenesis
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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