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Anti-CSNK2B Antibody EP1995Y
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Also for CSNK2B (NM_001320)
|A synthetic peptide corresponding to residues near the C-terminal of human CKII beta protein was used as an immunogen.|
|Human, Mouse, Rat
|WB, IHC, IF
||FC: 1:20, ICC: 1:100, IHC: 1:100, WB: 1:500 - 2000,
|Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.|
|Homo sapiens casein kinase 2, beta polypeptide (CSNK2B)|
|CK2B; CK2N; CSK2B; G5A|
|Casein Kinase II (CKII, CK2, phosvitin kinase, troponin T kinase, casein kinase G) is a ubiquitous serine/threonine protein kinase that is highly conserved and commonly found in eukaryotic cells (found in the cytoplasm and the nucleus). CKII is a heterotetramer that consists of two catalytic subunits (alpha, alpha-prime) and two regulatory beta subunits (1). CKII can utilize both GTP and ATP as the phosphate donor and phosphorylates threonine and serine residues. Therefore, CKII is a multifunctional protein kinase with broad range of substrates (e.g. c-Myc, c-Myb, c-Fos, c-Jun, p53, Rb, HPVE7) and it has been implicated in various cell functions/processes from cell transformation to mitosis. (2) |
Wnt Signaling Pathway
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A. Western blot analysis using anti-Casein Kinase II (beta subunit) RabMAb on K562 cell lysate .
C. Immunohistochemical analysis of paraffin-embedded human ovary carcinoma using anti-Casein Kinase RabMAb.
B. Immunofluorescent staining of HeLa cells using anti-Casein Kinase RabMAb .