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Home Antibody All anti-CRK antibodies

Anti-CRK PHOSPHO Antibody

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SKU Description Amount Price Availability*  
TA325391 Rabbit Polyclonal CrkII (Tyr221) Antibody (Phospho-specific) 100ul $325 In Stock
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WB(1)

OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human CrkII around the phosphorylation site of Tyrosine 221
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; IF/ICC: 1:100-1:500
Predicted MW Explanation 42kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens v-crk avian sarcoma virus CT10 oncogene homolog (CRK), transcript variant I
Alternative NameCRKII; p38
Database LinkNP_005197
Entrez Gene 1398 Human
Entrez Gene 12928 Mouse
Entrez Gene 54245 Rat
FunctionCrk an adaptor protein with an SH2-SH3-SH3 domain structure. Recruits cytoplasmic proteins through SH2-phospho-tyrosine interaction. Phosphorylated by Abl, IGF-IR and EGFR.
Related PathwayTranscription FactorsDruggable Genome MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayFocal adhesionFc gamma R-mediated phagocytosisNeurotrophin signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of CrkII phosphorylation expression in COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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