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Anti-CRK PHOSPHO Antibody
|The antiserum was produced against A synthesized peptide derived from human CrkII around the phosphorylation site of Tyrosine 221|
|Human, Mouse, Rat
||WB: 1:500-1:2000; IF/ICC: 1:100-1:500
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens v-crk avian sarcoma virus CT10 oncogene homolog (CRK), transcript variant I|
|Crk an adaptor protein with an SH2-SH3-SH3 domain structure. Recruits cytoplasmic proteins through SH2-phospho-tyrosine interaction. Phosphorylated by Abl, IGF-IR and EGFR.|
EGFR1 Signaling Pathway
MAPK signaling pathway
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Western blot analysis of CrkII phosphorylation expression in COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.