Home Antibody All anti-CRHR1 antibodies
Also for CRHR1 (NM_001145146)
| Peptide with sequence C-NEEKKSKVHYH, from the internal region of the protein sequence according to NP_004373.2.|
|Test: Human, Mouse. Expected from seq similarity: Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||ELISA: 1:32,000, WB: 0.1-0.3µg/ml, IF: 2ug/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|This product was successfully used on cryosection of mouse brain
|Homo sapiens corticotropin releasing hormone receptor 1 (CRHR1), transcript variant 1|
|CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRH-R1h; CRHR; CRHR1f; CRHR1L|
|This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. |
Signaling by GPCR
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TA303282 (0.1µg/ml) staining of human colon lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Confocal image (3µm) of TA303282 (0.3µg/ml) staining in green a dendrite of a neuronal cell in C57 mouse cortex. Counter-stained with DAPI (in blue). Data kindly provided by Dr Y. Chen, TZ Baram lab, UC Irvine, CA.