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Home Antibody All anti-CREM antibodies

Anti-CREM Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302456 Goat Polyclonal Antibody against CREM 100ug $325 3-7 Days
LC403643 CREM HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenPeptide with sequence LETLKDICSPKTDY, from the C Terminus of the protein sequence according to NP_853549.1; NP_874387.1; NP_874388.1; NP_874393.1; NP_874394.1; NP_877570.1; NP_877571.1; NP_877572.1; NP_877573.1; NP_878270.1; NP_898883.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:16,000. WB: 1-3µg/ml.
Predicted MW Explanation 17108Da
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens cAMP responsive element modulator (CREM), transcript variant 6
Alternative NameCREM-2; hCREM-2; ICER
Database LinkNP_874388
Entrez Gene 1390 Human
Entrez Gene 12916 Mouse
Entrez Gene 25620 Rat
FunctionThis gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq].
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA302456 staining (1µg/ml) of human heart lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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