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Home Antibody All anti-CREB3 antibodies

Anti-CREB3 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320217 Goat Polyclonal CREB3 (aa76-87) Antibody 100ug $325 3-7 Days
LC416687 CREB3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenPeptide with sequence C-HHDHTYSLPRET, from the internal region of the protein sequence according to NP_006359.3
Clone Name IsotypeIgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.3-1ug/ml, ELISA: 1:128,000
Predicted MW Explanation 41.4kDa
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Reference Data

Target NameHomo sapiens cAMP responsive element binding protein 3 (CREB3)
Alternative NameLUMAN; LZIP; sLZIP
Database LinkNP_006359
Entrez Gene 10488 Human
FunctionThis gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.[provided by RefSeq, Nov 2009].
Related PathwayTranscription Factors MelanogenesisHuntington's diseaseProstate cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Anti-CREB3 (0.3ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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