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Home Antibody All anti-CRADD antibodies

Anti-CRADD Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305943
  • Rabbit Polyclonal RAIDD Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401252) , 20ug
100ug $325 3-7 Days
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WB(1)
IF(1)
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Also for CRADD (NM_003805)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRAIDD antibody was raised against a peptide corresponding to amino acids 99 to 117 of human RAIDD .
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens CASP2 and RIPK1 domain containing adaptor with death domain (CRADD)
Alternative NameMRT34; RAIDD
Database LinkNP_003796
FunctionApoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1,RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals1,3. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.
Related Pathway
Apoptosis

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WB Image
Western blot analysis of RAIDD in whole cell lysates from HeLa (H) or K562 (K) cells with RAIDD antibody at 1:500 dilution.
IF Image
Immunocytochemistry of RAIDD in HeLa cells with RAIDD antibody at 5 ug/mL.

 

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