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Home Antibody All anti-COPS5 antibodies

Anti-COPS5 Antibody EPR1350

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310344
  • Rabbit Monoclonal antibody against COPS5
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416392) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
Assay(1)
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Also for COPS5 (NM_006837)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human COPS5 was used as an immunogen.
Clone NameEPR1350 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC/IF: 1:50 - 1:100
Predicted MW Explanation 38 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens COP9 signalosome subunit 5 (COPS5)
Alternative NameCSN5; JAB1; MOV-34; SGN5
Database LinkNP_006828
Entrez Gene 10987 Human
Entrez Gene 26754 Mouse
Entrez Gene 312916 Rat
FunctionCOPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. COPS5 is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors (1).
Related PathwayProteaseTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-JAB1 antibody [EPR1350]; All lanes : Anti-JAB1 antibody [EPR1350] at 1/1000 dilution.Lane 1 : NIH 3T3 cell lysate.Lane 2 : U87-MG cell lysate.Lane 3 : MCF7 cell lysate.Lane 4 : PC12 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 38 kDa.
Assay Image
Other-Anti-JAB1 antibody [EPR1350](TA310344); Equilibrium disassociation constant (KD)..

 

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