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Home Antibody All anti-COMP antibodies

Anti-COMP Antibody EPR6289(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310341
  • Rabbit Monoclonal antibody against COMP
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424929) , 20ug Explanation
100ul 325 In Stock
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WB(1)
FC(1)
Assay(1)
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Also for COMP (NM_000095)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human COMP was used as an immunogen.
Clone NameEPR6289(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: Use at an assay dependent concentration; FC: 1:10 - 1:100; ICC/IF: Use at an assay dependent concentration
Predicted MW Explanation 82 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens cartilage oligomeric matrix protein (COMP)
Alternative NameEDM1; EPD1; MED; PSACH; THBS5
Database LinkNP_000086
Entrez Gene 1311 Human
Entrez Gene 12845 Mouse
Entrez Gene 25304 Rat
FunctionCOMP is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) (1).
Related PathwaySecreted ProteinDruggable Genome TGF-beta signaling pathwayFocal adhesionECM-receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-COMP antibody [EPR6289(2)]; All lanes : Anti-COMP antibody [EPR6289(2)] at 1/10000 dilution.Lane 1 : Raji cell lysate.Lane 2 : BxPC3 cell lysate.Lane 3 : Saos 2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 82 kDa.
Assay Image
Other-Anti-COMP antibody [EPR6289(2)](TA310341); Equilibrium disassociation constant (KD)..
FC Image
Flow Cytometry - Anti-COMP antibody [EPR6289(2)]; TA310341 at 1/10 dilution staining COMP in permeabilized Raji cells by Flow cytometry (red). Rabbit IgG negative control (green)

 

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