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Home Antibody All anti-CLDN14 antibodies

Anti-CLDN14 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302811
  • Goat Polyclonal Antibody against CLDN14
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415957) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for CLDN14 (NM_012130)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

Immunogen Peptide with sequence C-SATHSGYRLNDYV, from the C Terminus of the protein sequence according to NP_036262; NP_652763.
Clone Name IsotypeGoat IgG
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:128,000. WB: 1-3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens claudin 14 (CLDN14), transcript variant epsilon
Alternative NameDFNB29
Database LinkNP_036262
FunctionTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. Two transcript variants encoding the same protein have been found for this gene.
Related Pathway

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WB Image
TA302811 (1µg/ml) staining of human liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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