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Anti-CHUK PHOSPHO Antibody
Also for CHUK (NM_001278)
|The antiserum was produced against A synthesized peptide derived from human IKK- alpha around the phosphorylation site of Threonine 23|
|Human, Mouse, Rat
||WB: 1:500-1:2000; IHC: 1:50-1:200
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens conserved helix-loop-helix ubiquitous kinase (CHUK)|
|IKBKA; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16|
Entrez Gene 1147 Human
Entrez Gene 12675 Mouse
Entrez Gene 309361 Rat
|IKK-alpha a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B, leading to their dissociation from NF-kappa-B and ultimately to their degradation. Phosphorylated and activated downstream of growth factor receptors, IL1R, and TNFR by NAK, IRAK and NIK, respectively.|
MAPK signaling pathway
Toll-like receptor signaling pathway
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Western blot analysis of IKK- alpha phosphorylation expression in EGF treated MDA-MB-435 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.