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Home Antibody All anti-CHUK antibodies

Anti-CHUK PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA325382
  • Rabbit Polyclonal IKK- alpha (Thr23) Antibody (Phospho-specific)
100ul 325 In Stock
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WB(1)

OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human IKK- alpha around the phosphorylation site of Threonine 23
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; IHC: 1:50-1:200
Predicted MW Explanation 85kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens conserved helix-loop-helix ubiquitous kinase (CHUK)
Alternative NameIKBKA; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16
Database LinkNP_001269
Entrez Gene 1147 Human
Entrez Gene 12675 Mouse
Entrez Gene 309361 Rat
FunctionIKK-alpha a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B, leading to their dissociation from NF-kappa-B and ultimately to their degradation. Phosphorylated and activated downstream of growth factor receptors, IL1R, and TNFR by NAK, IRAK and NIK, respectively.
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayChemokine signaling pathwayApoptosisToll-like receptor signaling pathwayNOD-like receptor signaling pathwayRIG-I-like receptor signaling pathwayMore Pathways >>

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IKK- alpha phosphorylation expression in EGF treated MDA-MB-435 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

 

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