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Home Antibody All anti-CHUK antibodies

Anti-CHUK PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA325381
  • Rabbit Polyclonal IKK- alpha (Ser176) /IKK- beta (Ser177) Antibody (Phospho-specific)
100ul 325 In Stock
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WB(1)

OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human IKK- alpha /IKK- beta around the phosphorylation site of Serine 177
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; IHC: 1:50-1:200
Predicted MW Explanation 85kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens conserved helix-loop-helix ubiquitous kinase (CHUK)
Alternative NameIKBKA; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16
Database LinkNP_001269
Entrez Gene 1147 Human
Entrez Gene 12675 Mouse
Entrez Gene 309361 Rat
FunctionIKK-beta a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayChemokine signaling pathwayApoptosisToll-like receptor signaling pathwayNOD-like receptor signaling pathwayRIG-I-like receptor signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IKK- alpha /IKK- beta phosphorylation expression in TNF treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

 

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