Home Antibody All anti-CHIT1 antibodies
Also for CHIT1 (NM_003465)
|Peptide with sequence EHGPSPGQDTFCQGK, from the internal region (near C Terminus) of the protein sequence according to NP_003456.1.|
|Test: Human. Expected from seq similarity: Human
||Lot dependent; please refer to CoA along with shipment
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
|Homo sapiens chitinase 1 (chitotriosidase) (CHIT1), transcript variant 1|
|CHI3; CHIT; CHITD|
Entrez Gene 1118 Human
|Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. [provided by RefSeq]. |
|Secreted ProteinTransmembrane Amino sugar and nucleotide sugar metabolism|
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TA309549 (1µg/ml) staining of Daudi lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.