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Anti-CHEK2 PHOSPHO Antibody


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SKU Description Amount Price Availability*  
TA312768 Rabbit polyclonal Chk2 (Thr383) antibody(Phospho-specific) 100ul 325
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OriGene Data

ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Chk2 around the phosphorylation site of threonine 383 (M-R-TP-L-C).
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:500~1:3000, IF: 1:100~1:500, ELISA: 1:20000
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note Chk2 (Phospho-Thr383) antibody detects endogenous levels of Chk2 only when phosphorylated at threonine 383.

Reference Data

Target NameHomo sapiens checkpoint kinase 2 (CHEK2), transcript variant 2
Alternative NameCDS1; CHK2; hCds1; HuCds1; LFS2; PP1425; RAD53
Database LinkNP_665861
Entrez Gene 11200 Human
Entrez Gene 50883 Mouse
Entrez Gene 114212 Rat
Related PathwayProtein KinaseStem cell - PluripotencyDruggable Genome Cell cyclep53 signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of extracts from COS7 cells, treated with UV (30mins), using Chk2 (Phospho-Thr383) antibody.The lane on the right is treated with the synthesized peptide.

IF Image
Immunofluorescence analysis of HeLa cells, using Chk2 (Phospho-Thr383) antibody.The picture on the right is treated with the synthesized peptide.


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