Home Antibody All anti-CFH antibodies
|Synthetic peptide corresponding to a region within amino acids 527 and 618 of Factor H (Uniprot ID#P08603)|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens complement factor H (CFH), transcript variant 1|
|AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS|
Entrez Gene 3075 Human
|This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Secreted ProteinDruggable Genome Complement and coagulation cascades|
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Sample (30 ug of whole cell lysate). A: Molt-4 . 5% SDS PAGE. TA308548 diluted at 1:5000.
Immunohistochemical analysis of paraffin-embedded U373 xenograft, using Factor H(TA308548) antibody at 1:200 dilution.