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Home Antibody All anti-CFH antibodies

Anti-CFH Antibody

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SKU Description Amount Price Availability*  
TA308548 Rabbit polyclonal antibody to Complement factor H (complement factor H) 100ul $325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 527 and 618 of Factor H (Uniprot ID#P08603)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:1000-1:10000
Predicted MW Explanation 139kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens complement factor H (CFH), transcript variant 1
Alternative NameAHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS
Database LinkNP_000177
Entrez Gene 3075 Human
FunctionThis gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Related PathwaySecreted ProteinDruggable Genome Complement and coagulation cascades

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* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Molt-4 . 5% SDS PAGE. TA308548 diluted at 1:5000.
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Immunohistochemical analysis of paraffin-embedded U373 xenograft, using Factor H(TA308548) antibody at 1:200 dilution.
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