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Anti-CEACAM1 GAT Antibody Polyclonal
Generated by Genomic Immunization
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Also for CEACAM1 (NM_001712)
|DNA immunization. This antibody is specific for the N Terminus Region of the target protein.|
|Human , Rat , Monkey , Mouse
|WB, ELISA, IHC
|| WB 1:5000~20000, IHC 1:150,ELISA 1:100-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1), transcript variant 1|
|BGP; BGP1; BGPI|
Entrez Gene 634 Human
Entrez Gene 26365 Mouse
Entrez Gene 81613 Rat
|This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined.|
|TransmembraneDruggable Genome |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CEACAM1 (RC221096, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CEACAM1.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CEACAM1 polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
ELISA: CEACAM1 Antibody - Affinity Purified
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-CEACAM1 Rabbit Polyclonal antibody. (TA590096)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-CEACAM1 Rabbit Polyclonal antibody. (TA590096)
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-CEACAM1 Rabbit Polyclonal antibody. (TA590096)
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-CEACAM1 Rabbit Polyclonal antibody. (TA590096)
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-CEACAM1 Rabbit Polyclonal antibody. (TA590096)