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Home Antibody All anti-CDK2 antibodies

Anti-CDK2 TRUEMAB Antibody Clone OTI2F10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502808 CDK2 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10) 100ul $325 In Stock
LC419741 CDK2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502808 Carrier-free (BSA/glycerol-free) CDK2 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10) 100ug $450 3-4 weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IF(1)
FC(3)

OriGene Data

ImmunogenFull length human recombinant protein of human CDK2 (NP_001789) produced in HEK293T cell.
Clone NameClone OTI2F10 IsotypeIgG1
Species ReactivityHuman Concentration0.53 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 33.7 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 1
Alternative NameCDKN2; p33(CDK2)
Database LinkNP_001789
Entrez Gene 1017 Human
FunctionThe protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome Cell cycleOocyte meiosisp53 signaling pathwayProgesterone-mediated oocyte maturationPathways in cancerProstate cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDK2 (RC200494, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDK2.
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Anti-CDK2 mouse monoclonal antibody (TA502808) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CDK2(RC200494).
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HEK293T cells transfected with either RC200494 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CDK2 antibody(TA502808), and then analyzed by flow cytometry.
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Flow cytometric Analysis of Hela cells, using anti-CDK2 antibody(TA502808),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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Flow cytometric Analysis of Jurkat cells, using anti-CDK2 antibody(TA502808),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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