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Anti-CDH1 TRUEMAB Antibody Clone 1F3
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for CDH1 (NM_004360)
|Full length human recombinant protein of human CDH1 (NP_004351) produced in HEK293T cell.|
|Human , Dog
|| WB 1:2000~4000, IHC 1:500,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens cadherin 1, type 1, E-cadherin (epithelial) (CDH1)|
|Arc-1; CD324; CDHE; ECAD; LCAM; UVO|
|This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]. |
Wnt Signaling Pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH1 (RC220731, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH1.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CDH1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CDH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA800671)
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-CDH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA800671)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CDH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA800671)