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Home Antibody All anti-CDH1 antibodies

Anti-CDH1 TRUEMAB Antibody Clone OTI2D6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA800669 CDH1 (E Cadherin) mouse monoclonal antibody, clone OTI2D6 (formerly 2D6) 100ul $325 In Stock
LC401389 CDH1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF800669 Carrier-free (BSA/glycerol-free) CDH1 mouse monoclonal antibody, clone OTI2D6 (formerly 2D6) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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OriGene Data

ImmunogenFull length human recombinant protein of human CDH1 (NP_004351) produced in HEK293T cell.
Clone NameClone OTI2D6 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 94.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cadherin 1, type 1, E-cadherin (epithelial) (CDH1)
Alternative NameArc-1; CD324; CDHE; ECAD; LCAM; UVO
Database LinkNP_004351
Entrez Gene 999 Human
FunctionThis gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008].
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Adherens junctionPathogenic Escherichia coli infectionPathways in cancerEndometrial cancerThyroid cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH1 (RC220731, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH1.
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